What is Becker muscular dystrophy?
Muscular dystrophy (MD) are a group of genetic disorders, which causes muscular weakness. The type of Becker was first recognized in 1956 and is now known to be a much milder variant of Duchenne MD better known Becker MD is usually slowly progressive and affects only men.
What is the cause?A fault in a particular gene (dystrophin) carried on the x chromosome leads to the formation of a defective protein in muscle fibers. This protein also called dystrophin, is absent or severely abnormal Duchenne MD. In Becker MD, more soft fault makes the smaller dystrophin molecule (or sometimes more) or less abundant than normal. When the dystrophin is abnormal muscle fibers gradually decompose and muscles slowly become weaker. These anomalies of dystrophin in muscle provide a very good test for the diagnosis of Becker MD.